null

SMILES: Clc1cccc(-c2ccc(\C=C(/C#N)C(=O)Nc3cccc4ncccc34)o2)c1Cl

InChI Key: InChIKey=RFDDNINWPNXLOG-WYMLVPIESA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50216693   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NAD-dependent protein deacetylase sirtuin-2 (Homo sapiens (Human))	BDBM50216693 (2-cyano-3-(5-(2,3-dichlorophenyl)furan-2-yl)-N-(qu...) Show SMILES Clc1cccc(-c2ccc(\C=C(/C#N)C(=O)Nc3cccc4ncccc34)o2)c1Cl Show InChI InChI=1S/C23H13Cl2N3O2/c24-18-6-1-4-17(22(18)25)21-10-9-15(30-21)12-14(13-26)23(29)28-20-8-2-7-19-16(20)5-3-11-27-19/h1-12H,(H,28,29)/b14-12+	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT2 using fluorescent peptide substrate by fluorescent assay				Science 317: 516-9 (2007) Article DOI: 10.1126/science.1143780 BindingDB Entry DOI: 10.7270/Q2D50MPG
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-1 (Homo sapiens (Human))	BDBM50216693 (2-cyano-3-(5-(2,3-dichlorophenyl)furan-2-yl)-N-(qu...) Show SMILES Clc1cccc(-c2ccc(\C=C(/C#N)C(=O)Nc3cccc4ncccc34)o2)c1Cl Show InChI InChI=1S/C23H13Cl2N3O2/c24-18-6-1-4-17(22(18)25)21-10-9-15(30-21)12-14(13-26)23(29)28-20-8-2-7-19-16(20)5-3-11-27-19/h1-12H,(H,28,29)/b14-12+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT1 using fluorescent peptide substrate by fluorescent assay				Science 317: 516-9 (2007) Article DOI: 10.1126/science.1143780 BindingDB Entry DOI: 10.7270/Q2D50MPG
					More data for this Ligand-Target Pair
NAD-dependent protein deacetylase sirtuin-3, mitochondrial (Homo sapiens (Human))	BDBM50216693 (2-cyano-3-(5-(2,3-dichlorophenyl)furan-2-yl)-N-(qu...) Show SMILES Clc1cccc(-c2ccc(\C=C(/C#N)C(=O)Nc3cccc4ncccc34)o2)c1Cl Show InChI InChI=1S/C23H13Cl2N3O2/c24-18-6-1-4-17(22(18)25)21-10-9-15(30-21)12-14(13-26)23(29)28-20-8-2-7-19-16(20)5-3-11-27-19/h1-12H,(H,28,29)/b14-12+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Harvard Medical School Curated by ChEMBL					Assay Description Inhibition of human recombinant SIRT3 using fluorescent peptide substrate by fluorescent assay				Science 317: 516-9 (2007) Article DOI: 10.1126/science.1143780 BindingDB Entry DOI: 10.7270/Q2D50MPG
					More data for this Ligand-Target Pair