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SMILES: COc1ccc(cc1)-c1ccc2ccc(C)nc2c1

InChI Key: InChIKey=NCNHXSMXZZAGHM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50216763   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))		BDBM50216763
PNG
(7-(4-methoxyphenyl)-2-methylquinoline | CHEMBL3961...)
Show SMILES COc1ccc(cc1)-c1ccc2ccc(C)nc2c1
Show InChI InChI=1S/C17H15NO/c1-12-3-4-14-5-6-15(11-17(14)18-12)13-7-9-16(19-2)10-8-13/h3-11H,1-2H3
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MMDB

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Article
PubMed
n/an/a 1.60E+4n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Activity at rat mGlu5 receptor expressed in CHO cells assessed as inhibition of quisqualate-stimulated calcium mobilization by FLIPR assay

Bioorg Med Chem Lett 17: 4415-8 (2007)


Article DOI: 10.1016/j.bmcl.2007.06.030
BindingDB Entry DOI: 10.7270/Q28G8KDC
More data for this
Ligand-Target Pair