BindingDB logo
myBDB logout

null

SMILES: NC(=N)NCCC[C@@H]1[C@H](N(C(=O)NCc2ccccc2)C1=O)C(O)=O

InChI Key: InChIKey=KHJFVHKEUJVWIV-NEPJUHHUSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50217598   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tryptase delta


(Homo sapiens (Human))		BDBM50217598
PNG
(CHEMBL320529)
Show SMILES NC(=N)NCCC[C@@H]1[C@H](N(C(=O)NCc2ccccc2)C1=O)C(O)=O
Show InChI InChI=1S/C16H21N5O4/c17-15(18)19-8-4-7-11-12(14(23)24)21(13(11)22)16(25)20-9-10-5-2-1-3-6-10/h1-3,5-6,11-12H,4,7-9H2,(H,20,25)(H,23,24)(H4,17,18,19)/t11-,12+/m1/s1
UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

Similars
PubMed
n/an/a 71n/an/an/an/an/an/a



The Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
In vitro inhibition of human tryptase.

Bioorg Med Chem Lett 12: 3229-33 (2002)


BindingDB Entry DOI: 10.7270/Q2QC05PZ
More data for this
Ligand-Target Pair