BDBM50218380 CHEMBL236102::N1-(5-6-(2,4-dichloro-5-fluorophenyl)-7-[(Z)-1-phenylmethylidene]-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-3-yl-4-phenyl-2-thienyl)acetamide

SMILES: CC(=O)Nc1cc(c(s1)-c1nnc2S\C(=C/c3ccccc3)C(=Nn12)c1cc(F)c(Cl)cc1Cl)-c1ccccc1

InChI Key: InChIKey=CRNLIDJMKWFHLG-MSXFZWOLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218380   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-Dependent Kinase 5 (CDK5) (Homo sapiens (Human))	BDBM50218380 (CHEMBL236102 | N1-(5-6-(2,4-dichloro-5-fluoropheny...) Show SMILES CC(=O)Nc1cc(c(s1)-c1nnc2S\C(=C/c3ccccc3)C(=Nn12)c1cc(F)c(Cl)cc1Cl)-c1ccccc1 |c:24| Show InChI InChI=1S/C29H18Cl2FN5OS2/c1-16(38)33-25-14-19(18-10-6-3-7-11-18)27(40-25)28-34-35-29-37(28)36-26(20-13-23(32)22(31)15-21(20)30)24(39-29)12-17-8-4-2-5-9-17/h2-15H,1H3,(H,33,38)/b24-12-	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a
Dr. Reddy's Laboratories Curated by ChEMBL					Assay Description Inhibitory activity against Cdk5/p25				Bioorg Med Chem 15: 6397-406 (2007) Article DOI: 10.1016/j.bmc.2007.06.053 BindingDB Entry DOI: 10.7270/Q2JS9RP0
					More data for this Ligand-Target Pair