BDBM50218595 CHEMBL117380

SMILES: Clc1cccc(Cl)c1NCc1c[nH]cn1

InChI Key: InChIKey=PUANXNMRUKASLN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50218595   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat))	BDBM50218595 (CHEMBL117380) Show SMILES Clc1cccc(Cl)c1NCc1c[nH]cn1 Show InChI InChI=1S/C10H9Cl2N3/c11-8-2-1-3-9(12)10(8)14-5-7-4-13-6-15-7/h1-4,6,14H,5H2,(H,13,15)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	263	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Inhibition of binding of [3H]-prazosin at alpha1 adrenoceptors isolated from rat brain				Bioorg Med Chem Lett 12: 3449-52 (2002) BindingDB Entry DOI: 10.7270/Q2G44RM1
					More data for this Ligand-Target Pair