BDBM50219280 5-(4-(chloromethyl)-5-methyloxazol-2-yl)-8-methoxy-2-(trifluoromethyl)quinoline::CHEMBL251298

SMILES: COc1ccc(-c2nc(CCl)c(C)o2)c2ccc(nc12)C(F)(F)F

InChI Key: InChIKey=AJKZDULCTIIISF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50219280   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50219280 (5-(4-(chloromethyl)-5-methyloxazol-2-yl)-8-methoxy...) Show SMILES COc1ccc(-c2nc(CCl)c(C)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C16H12ClF3N2O2/c1-8-11(7-17)21-15(24-8)10-3-5-12(23-2)14-9(10)4-6-13(22-14)16(18,19)20/h3-6H,7H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 17: 5150-4 (2007) Article DOI: 10.1016/j.bmcl.2007.06.092 BindingDB Entry DOI: 10.7270/Q2862G4H
					More data for this Ligand-Target Pair