BDBM50219284 (5-(aminomethyl)-2-(8-methoxy-2-(trifluoromethyl)quinolin-5-yl)oxazol-4-yl)(pyrrolidin-1-yl)methanone::CHEMBL401121

SMILES: COc1ccc(-c2nc(C(=O)N3CCCC3)c(CN)o2)c2ccc(nc12)C(F)(F)F

InChI Key: InChIKey=GDIRJTNQDBKWFH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50219284   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
3',5'-cyclic phosphodiesterase (Homo sapiens (Human))	BDBM50219284 ((5-(aminomethyl)-2-(8-methoxy-2-(trifluoromethyl)q...) Show SMILES COc1ccc(-c2nc(C(=O)N3CCCC3)c(CN)o2)c2ccc(nc12)C(F)(F)F Show InChI InChI=1S/C20H19F3N4O3/c1-29-13-6-4-12(11-5-7-15(20(21,22)23)25-16(11)13)18-26-17(14(10-24)30-18)19(28)27-8-2-3-9-27/h4-7H,2-3,8-10,24H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of PDE4B				Bioorg Med Chem Lett 17: 5150-4 (2007) Article DOI: 10.1016/j.bmcl.2007.06.092 BindingDB Entry DOI: 10.7270/Q2862G4H
					More data for this Ligand-Target Pair