BDBM50219877 CHEMBL246221::N-(2-((2S,3R)-3-(2,4-dimethylbenzylamino)-1-(ethylamino)-1-oxobutan-2-ylamino)-2-oxoethyl)-3-(trifluoromethyl)benzamide

SMILES: CCNC(=O)[C@@H](NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F)[C@@H](C)NCc1ccc(C)cc1C

InChI Key: InChIKey=RNGBECAFIOPBQI-VGSWGCGISA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50219877   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM50219877 (CHEMBL246221 | N-(2-((2S,3R)-3-(2,4-dimethylbenzyl...) Show SMILES CCNC(=O)[C@@H](NC(=O)CNC(=O)c1cccc(c1)C(F)(F)F)[C@@H](C)NCc1ccc(C)cc1C Show InChI InChI=1S/C25H31F3N4O3/c1-5-29-24(35)22(17(4)30-13-19-10-9-15(2)11-16(19)3)32-21(33)14-31-23(34)18-7-6-8-20(12-18)25(26,27)28/h6-12,17,22,30H,5,13-14H2,1-4H3,(H,29,35)(H,31,34)(H,32,33)/t17-,22+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company Curated by ChEMBL					Assay Description Displacement of [125]MCP1 from CCR2 in human PBMCs				Bioorg Med Chem Lett 17: 5455-61 (2007) Article DOI: 10.1016/j.bmcl.2007.07.028 BindingDB Entry DOI: 10.7270/Q29Z94NN
					More data for this Ligand-Target Pair