BDBM50219939 CHEMBL240693::N-((1r,4r)-4-(2-(4-(2,3-dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)pyridine-3-sulfonamide
SMILES: Clc1cccc(N2CCN(CC[C@H]3CC[C@@H](CC3)NS(=O)(=O)c3cccnc3)CC2)c1Cl
InChI Key: InChIKey=DLCUNIPVNVPKEI-WGSAOQKQSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
D(3) dopamine receptor (Rattus norvegicus (Rat)) | BDBM50219939 (CHEMBL240693 | N-((1r,4r)-4-(2-(4-(2,3-dichlorophe...) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
Gedeon Richter Ltd Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from rat dopamine D3 receptor expressed in Sf9 cells | Bioorg Med Chem Lett 17: 5340-4 (2007) Article DOI: 10.1016/j.bmcl.2007.08.015 BindingDB Entry DOI: 10.7270/Q22F7N5G | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
D(2) dopamine receptor (Rattus norvegicus (rat)) | BDBM50219939 (CHEMBL240693 | N-((1r,4r)-4-(2-(4-(2,3-dichlorophe...) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Gedeon Richter Ltd Curated by ChEMBL | Assay Description Displacement of [3H]spiperone from dopamine D2 receptor in rat striatal membranes | Bioorg Med Chem Lett 17: 5340-4 (2007) Article DOI: 10.1016/j.bmcl.2007.08.015 BindingDB Entry DOI: 10.7270/Q22F7N5G | |||||||||||
More data for this Ligand-Target Pair |