BDBM50220026 (5R)-3-(3-fluoro-4-{6-[(2-methyl-1H-imidazol-1-yl)acetyl]pyridin-3-yl}phenyl)-5-(1H-1,2,3-triazol-1-ylmethyl)-1,3-oxazolidin-2-one::CHEMBL388012

SMILES: Cc1nccn1CC(=O)c1ccc(cn1)-c1ccc(cc1F)N1C[C@H](Cn2ccnn2)OC1=O

InChI Key: InChIKey=ITMSPKNBOCNPGW-SFHVURJKSA-N

Data: 1 KI  5 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50220026   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Amine oxidase (flavin-containing) A (Homo sapiens (Human))	BDBM50220026 ((5R)-3-(3-fluoro-4-{6-[(2-methyl-1H-imidazol-1-yl)...) Show SMILES Cc1nccn1CC(=O)c1ccc(cn1)-c1ccc(cc1F)N1C[C@H](Cn2ccnn2)OC1=O Show InChI InChI=1S/C23H20FN7O3/c1-15-25-6-8-29(15)14-22(32)21-5-2-16(11-26-21)19-4-3-17(10-20(19)24)31-13-18(34-23(31)33)12-30-9-7-27-28-30/h2-11,18H,12-14H2,1H3/t18-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>8.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Discovery Curated by ChEMBL					Assay Description Inhibition of human liver MAOA expressed in yeast				J Med Chem 50: 4868-81 (2007) Article DOI: 10.1021/jm070428+ BindingDB Entry DOI: 10.7270/Q2SX6CX0
					More data for this Ligand-Target Pair
Cytochrome P450 2C9 (Homo sapiens (Human))	BDBM50220026 ((5R)-3-(3-fluoro-4-{6-[(2-methyl-1H-imidazol-1-yl)...) Show SMILES Cc1nccn1CC(=O)c1ccc(cn1)-c1ccc(cc1F)N1C[C@H](Cn2ccnn2)OC1=O Show InChI InChI=1S/C23H20FN7O3/c1-15-25-6-8-29(15)14-22(32)21-5-2-16(11-26-21)19-4-3-17(10-20(19)24)31-13-18(34-23(31)33)12-30-9-7-27-28-30/h2-11,18H,12-14H2,1H3/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Discovery Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP2C9				J Med Chem 50: 4868-81 (2007) Article DOI: 10.1021/jm070428+ BindingDB Entry DOI: 10.7270/Q2SX6CX0
					More data for this Ligand-Target Pair
Cytochrome P450 2C19 (Homo sapiens (Human))	BDBM50220026 ((5R)-3-(3-fluoro-4-{6-[(2-methyl-1H-imidazol-1-yl)...) Show SMILES Cc1nccn1CC(=O)c1ccc(cn1)-c1ccc(cc1F)N1C[C@H](Cn2ccnn2)OC1=O Show InChI InChI=1S/C23H20FN7O3/c1-15-25-6-8-29(15)14-22(32)21-5-2-16(11-26-21)19-4-3-17(10-20(19)24)31-13-18(34-23(31)33)12-30-9-7-27-28-30/h2-11,18H,12-14H2,1H3/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Discovery Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP2C19				J Med Chem 50: 4868-81 (2007) Article DOI: 10.1021/jm070428+ BindingDB Entry DOI: 10.7270/Q2SX6CX0
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50220026 ((5R)-3-(3-fluoro-4-{6-[(2-methyl-1H-imidazol-1-yl)...) Show SMILES Cc1nccn1CC(=O)c1ccc(cn1)-c1ccc(cc1F)N1C[C@H](Cn2ccnn2)OC1=O Show InChI InChI=1S/C23H20FN7O3/c1-15-25-6-8-29(15)14-22(32)21-5-2-16(11-26-21)19-4-3-17(10-20(19)24)31-13-18(34-23(31)33)12-30-9-7-27-28-30/h2-11,18H,12-14H2,1H3/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Discovery Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP3A4				J Med Chem 50: 4868-81 (2007) Article DOI: 10.1021/jm070428+ BindingDB Entry DOI: 10.7270/Q2SX6CX0
					More data for this Ligand-Target Pair
Cytochrome P450 1A (Homo sapiens (Human))	BDBM50220026 ((5R)-3-(3-fluoro-4-{6-[(2-methyl-1H-imidazol-1-yl)...) Show SMILES Cc1nccn1CC(=O)c1ccc(cn1)-c1ccc(cc1F)N1C[C@H](Cn2ccnn2)OC1=O Show InChI InChI=1S/C23H20FN7O3/c1-15-25-6-8-29(15)14-22(32)21-5-2-16(11-26-21)19-4-3-17(10-20(19)24)31-13-18(34-23(31)33)12-30-9-7-27-28-30/h2-11,18H,12-14H2,1H3/t18-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Discovery Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP1A2				J Med Chem 50: 4868-81 (2007) Article DOI: 10.1021/jm070428+ BindingDB Entry DOI: 10.7270/Q2SX6CX0
					More data for this Ligand-Target Pair
Cytochrome P450 2D6 (Homo sapiens (Human))	BDBM50220026 ((5R)-3-(3-fluoro-4-{6-[(2-methyl-1H-imidazol-1-yl)...) Show SMILES Cc1nccn1CC(=O)c1ccc(cn1)-c1ccc(cc1F)N1C[C@H](Cn2ccnn2)OC1=O Show InChI InChI=1S/C23H20FN7O3/c1-15-25-6-8-29(15)14-22(32)21-5-2-16(11-26-21)19-4-3-17(10-20(19)24)31-13-18(34-23(31)33)12-30-9-7-27-28-30/h2-11,18H,12-14H2,1H3/t18-/m0/s1	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Discovery Curated by ChEMBL					Assay Description Inhibition of human recombinant CYP2D6				J Med Chem 50: 4868-81 (2007) Article DOI: 10.1021/jm070428+ BindingDB Entry DOI: 10.7270/Q2SX6CX0
					More data for this Ligand-Target Pair