BDBM50220362 (+/-)-tetrahydro-2H-pyran-2-ylmethyl (9Z,12Z,15Z)-octadeca-9,12,15-trienoate::CHEMBL230969
SMILES: CC\C=C/C\C=C/C\C=C/CCCCCCCC(=O)OCC1CCCCO1
InChI Key: InChIKey=DJZYWZIMMYMFKD-PDBXOOCHSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Fatty-acid amide hydrolase 1 (aa 30-579) (Rattus norvegicus (rat)) | BDBM50220362 ((+/-)-tetrahydro-2H-pyran-2-ylmethyl (9Z,12Z,15Z)-...) | PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.90E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense Curated by ChEMBL | Assay Description Inhibition of FAAH in rat cerebellum membranes assessed as [3H]anandamide hydrolysis | J Med Chem 50: 5012-23 (2007) Article DOI: 10.1021/jm070642y BindingDB Entry DOI: 10.7270/Q2N879HC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Monoglyceride lipase (MGL) (Rattus norvegicus (Rat)) | BDBM50220362 ((+/-)-tetrahydro-2H-pyran-2-ylmethyl (9Z,12Z,15Z)-...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidad Complutense Curated by ChEMBL | Assay Description Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis | J Med Chem 50: 5012-23 (2007) Article DOI: 10.1021/jm070642y BindingDB Entry DOI: 10.7270/Q2N879HC | |||||||||||
More data for this Ligand-Target Pair |