BDBM50220675 CHEMBL47362

SMILES: CC(C)(C)NC(=O)C(=O)Nc1ccc(-c2cnco2)c(c1)C(F)(F)F

InChI Key: InChIKey=KVPNOVRBBQDQQE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220675   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Inosine-5'-monophosphate dehydrogenase (IMPDH) (Homo sapiens (Human))	BDBM50220675 (CHEMBL47362) Show SMILES CC(C)(C)NC(=O)C(=O)Nc1ccc(-c2cnco2)c(c1)C(F)(F)F Show InChI InChI=1S/C16H16F3N3O3/c1-15(2,3)22-14(24)13(23)21-9-4-5-10(12-7-20-8-25-12)11(6-9)16(17,18)19/h4-8H,1-3H3,(H,21,23)(H,22,24)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Roche Discovery Welwyn Curated by ChEMBL					Assay Description Inhibitory activity against (IMPDH) inosine 5'-monophosphate dehydrogenase				Bioorg Med Chem Lett 13: 1691-4 (2003) BindingDB Entry DOI: 10.7270/Q21N83B7
					More data for this Ligand-Target Pair