BDBM50220729 CHEMBL237320::N-((1s,4s)-4-hydroxy-4-(4-hydroxyphenyl)cyclohexyl)-3-phenylpropanamide

SMILES: Oc1ccc(cc1)[C@@]1(O)CC[C@@H](CC1)NC(=O)CCc1ccccc1

InChI Key: InChIKey=JIHJKNMBUYNINN-RVWIWJKTSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50220729   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50220729 (CHEMBL237320 | N-((1s,4s)-4-hydroxy-4-(4-hydroxyph...) Show SMILES Oc1ccc(cc1)[C@@]1(O)CC[C@@H](CC1)NC(=O)CCc1ccccc1 |wD:7.8,11.15,(10.84,-24.52,;12.17,-23.76,;12.17,-22.2,;13.49,-21.43,;14.83,-22.2,;14.84,-23.74,;13.52,-24.52,;16.17,-21.43,;16.15,-22.96,;16.17,-19.89,;17.49,-19.1,;18.83,-19.89,;18.83,-21.43,;17.49,-22.2,;20.17,-19.12,;21.5,-19.89,;21.5,-21.44,;22.85,-19.13,;24.17,-19.91,;25.51,-19.15,;26.82,-19.93,;28.17,-19.18,;28.17,-17.63,;26.86,-16.86,;25.52,-17.61,)| Show InChI InChI=1S/C21H25NO3/c23-19-9-7-17(8-10-19)21(25)14-12-18(13-15-21)22-20(24)11-6-16-4-2-1-3-5-16/h1-5,7-10,18,23,25H,6,11-15H2,(H,22,24)/t18-,21+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Displacement of [3H]dofetilide from human HERG expressed in HEK293 cells				Bioorg Med Chem Lett 17: 5533-6 (2007) Article DOI: 10.1016/j.bmcl.2007.08.039 BindingDB Entry DOI: 10.7270/Q23778FR
					More data for this Ligand-Target Pair
Glutamate receptor ionotropic, NMDA 2B (Rattus norvegicus (Rat))	BDBM50220729 (CHEMBL237320 | N-((1s,4s)-4-hydroxy-4-(4-hydroxyph...) Show SMILES Oc1ccc(cc1)[C@@]1(O)CC[C@@H](CC1)NC(=O)CCc1ccccc1 |wD:7.8,11.15,(10.84,-24.52,;12.17,-23.76,;12.17,-22.2,;13.49,-21.43,;14.83,-22.2,;14.84,-23.74,;13.52,-24.52,;16.17,-21.43,;16.15,-22.96,;16.17,-19.89,;17.49,-19.1,;18.83,-19.89,;18.83,-21.43,;17.49,-22.2,;20.17,-19.12,;21.5,-19.89,;21.5,-21.44,;22.85,-19.13,;24.17,-19.91,;25.51,-19.15,;26.82,-19.93,;28.17,-19.18,;28.17,-17.63,;26.86,-16.86,;25.52,-17.61,)| Show InChI InChI=1S/C21H25NO3/c23-19-9-7-17(8-10-19)21(25)14-12-18(13-15-21)22-20(24)11-6-16-4-2-1-3-5-16/h1-5,7-10,18,23,25H,6,11-15H2,(H,22,24)/t18-,21+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research & Development Curated by ChEMBL					Assay Description Displacement of [3H]CP101,606 from NR2B in rat forebrain P2 membrane				Bioorg Med Chem Lett 17: 5533-6 (2007) Article DOI: 10.1016/j.bmcl.2007.08.039 BindingDB Entry DOI: 10.7270/Q23778FR
					More data for this Ligand-Target Pair