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BDBM50220932 1-(adamantan-1-ylamino)-4-(1H-indol-4-yloxy)-butan-2-ol::CHEMBL236517

SMILES: OC(CCOc1cccc2[nH]ccc12)CNC12CC3CC(CC(C3)C1)C2

InChI Key: InChIKey=GSFWJKZNVNNKLE-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50220932   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 1A


(Homo sapiens (Human))		BDBM50220932
PNG
(1-(adamantan-1-ylamino)-4-(1H-indol-4-yloxy)-butan...)
Show SMILES OC(CCOc1cccc2[nH]ccc12)CNC12CC3CC(CC(C3)C1)C2 |w:1.0,TLB:15:16:19:23.21.22,THB:21:20:17:23.22.24,21:22:19.20.25:17,24:22:19:25.16.17,24:16:19:23.21.22|
Show InChI InChI=1S/C22H30N2O2/c25-18(5-7-26-21-3-1-2-20-19(21)4-6-23-20)14-24-22-11-15-8-16(12-22)10-17(9-15)13-22/h1-4,6,15-18,23-25H,5,7-14H2
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Article
PubMed
 551n/an/an/an/an/an/an/an/a



Lilly Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [3H]DPAT from human 5HT1A receptor

Bioorg Med Chem Lett 17: 5600-4 (2007)


Article DOI: 10.1016/j.bmcl.2007.07.086
BindingDB Entry DOI: 10.7270/Q2FJ2GG0
More data for this
Ligand-Target Pair