BDBM50221122 CHEMBL441136::N-((S)-1-(2-(4-((R)-3-(2,4-dichlorophenyl)-2-(2-oxopyrrolidin-1-yl)propanoyl)piperazin-1-yl)-5-fluorophenyl)-3-methylbutyl)-2-(methylamino)acetamide

SMILES: CNCC(=O)N[C@@H](CC(C)C)c1cc(F)ccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)N1CCCC1=O

InChI Key: InChIKey=ZVXDTQBHPOHGTP-XTEPFMGCSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221122   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50221122 (CHEMBL441136 | N-((S)-1-(2-(4-((R)-3-(2,4-dichloro...) Show SMILES CNCC(=O)N[C@@H](CC(C)C)c1cc(F)ccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)N1CCCC1=O Show InChI InChI=1S/C31H40Cl2FN5O3/c1-20(2)15-26(36-29(40)19-35-3)24-18-23(34)8-9-27(24)37-11-13-38(14-12-37)31(42)28(39-10-4-5-30(39)41)16-21-6-7-22(32)17-25(21)33/h6-9,17-18,20,26,28,35H,4-5,10-16,19H2,1-3H3,(H,36,40)/t26-,28+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity at human MC4R				Bioorg Med Chem Lett 17: 5610-3 (2007) Article DOI: 10.1016/j.bmcl.2007.07.097 BindingDB Entry DOI: 10.7270/Q2XK8F8V
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50221122 (CHEMBL441136 | N-((S)-1-(2-(4-((R)-3-(2,4-dichloro...) Show SMILES CNCC(=O)N[C@@H](CC(C)C)c1cc(F)ccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)N1CCCC1=O Show InChI InChI=1S/C31H40Cl2FN5O3/c1-20(2)15-26(36-29(40)19-35-3)24-18-23(34)8-9-27(24)37-11-13-38(14-12-37)31(42)28(39-10-4-5-30(39)41)16-21-6-7-22(32)17-25(21)33/h6-9,17-18,20,26,28,35H,4-5,10-16,19H2,1-3H3,(H,36,40)/t26-,28+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of microsomal CYP3A4				Bioorg Med Chem Lett 17: 5610-3 (2007) Article DOI: 10.1016/j.bmcl.2007.07.097 BindingDB Entry DOI: 10.7270/Q2XK8F8V
					More data for this Ligand-Target Pair