BDBM50221382 CHEMBL394189::N-{4-[4-(diphenylmethyl)-1,4-diazepan-1-yl]butyl}-naphthalen-2-carboxamide

SMILES: O=C(NCCCCN1CCCN(CC1)C(c1ccccc1)c1ccccc1)c1ccc2ccccc2c1

InChI Key: InChIKey=LDYSMWZYEMTWHM-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50221382   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50221382 (CHEMBL394189 | N-{4-[4-(diphenylmethyl)-1,4-diazep...) Show SMILES O=C(NCCCCN1CCCN(CC1)C(c1ccccc1)c1ccccc1)c1ccc2ccccc2c1 Show InChI InChI=1S/C33H37N3O/c37-33(31-19-18-27-12-7-8-17-30(27)26-31)34-20-9-10-21-35-22-11-23-36(25-24-35)32(28-13-3-1-4-14-28)29-15-5-2-6-16-29/h1-8,12-19,26,32H,9-11,20-25H2,(H,34,37)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	32.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human D3 receptor expressed in CHO cells				Bioorg Med Chem 15: 7258-73 (2007) Article DOI: 10.1016/j.bmc.2007.08.034 BindingDB Entry DOI: 10.7270/Q21C1WMX
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50221382 (CHEMBL394189 | N-{4-[4-(diphenylmethyl)-1,4-diazep...) Show SMILES O=C(NCCCCN1CCCN(CC1)C(c1ccccc1)c1ccccc1)c1ccc2ccccc2c1 Show InChI InChI=1S/C33H37N3O/c37-33(31-19-18-27-12-7-8-17-30(27)26-31)34-20-9-10-21-35-22-11-23-36(25-24-35)32(28-13-3-1-4-14-28)29-15-5-2-6-16-29/h1-8,12-19,26,32H,9-11,20-25H2,(H,34,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	136	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human dopamine D2S receptor expressed in HEK cells				Bioorg Med Chem 15: 7258-73 (2007) Article DOI: 10.1016/j.bmc.2007.08.034 BindingDB Entry DOI: 10.7270/Q21C1WMX
					More data for this Ligand-Target Pair