BDBM50221448 (R)-3-amino-1-(2-phenyl-5,6-dihydro-[1,2,4]triazolo[1,5-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)butan-1-one::CHEMBL401057

SMILES: N[C@@H](CC(=O)N1CCn2nc(nc2C1)-c1ccccc1)Cc1cc(F)c(F)cc1F

InChI Key: InChIKey=VCTJXCYUKWWVIH-OAHLLOKOSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50221448   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50221448 ((R)-3-amino-1-(2-phenyl-5,6-dihydro-[1,2,4]triazol...) Show SMILES N[C@@H](CC(=O)N1CCn2nc(nc2C1)-c1ccccc1)Cc1cc(F)c(F)cc1F Show InChI InChI=1S/C21H20F3N5O/c22-16-11-18(24)17(23)9-14(16)8-15(25)10-20(30)28-6-7-29-19(12-28)26-21(27-29)13-4-2-1-3-5-13/h1-5,9,11,15H,6-8,10,12,25H2/t15-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP4				Bioorg Med Chem Lett 17: 5934-9 (2007) Article DOI: 10.1016/j.bmcl.2007.07.100 BindingDB Entry DOI: 10.7270/Q20C4VH0
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50221448 ((R)-3-amino-1-(2-phenyl-5,6-dihydro-[1,2,4]triazol...) Show SMILES N[C@@H](CC(=O)N1CCn2nc(nc2C1)-c1ccccc1)Cc1cc(F)c(F)cc1F Show InChI InChI=1S/C21H20F3N5O/c22-16-11-18(24)17(23)9-14(16)8-15(25)10-20(30)28-6-7-29-19(12-28)26-21(27-29)13-4-2-1-3-5-13/h1-5,9,11,15H,6-8,10,12,25H2/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP8				Bioorg Med Chem Lett 17: 5934-9 (2007) Article DOI: 10.1016/j.bmcl.2007.07.100 BindingDB Entry DOI: 10.7270/Q20C4VH0
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50221448 ((R)-3-amino-1-(2-phenyl-5,6-dihydro-[1,2,4]triazol...) Show SMILES N[C@@H](CC(=O)N1CCn2nc(nc2C1)-c1ccccc1)Cc1cc(F)c(F)cc1F Show InChI InChI=1S/C21H20F3N5O/c22-16-11-18(24)17(23)9-14(16)8-15(25)10-20(30)28-6-7-29-19(12-28)26-21(27-29)13-4-2-1-3-5-13/h1-5,9,11,15H,6-8,10,12,25H2/t15-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of DPP9				Bioorg Med Chem Lett 17: 5934-9 (2007) Article DOI: 10.1016/j.bmcl.2007.07.100 BindingDB Entry DOI: 10.7270/Q20C4VH0
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM50221448 ((R)-3-amino-1-(2-phenyl-5,6-dihydro-[1,2,4]triazol...) Show SMILES N[C@@H](CC(=O)N1CCn2nc(nc2C1)-c1ccccc1)Cc1cc(F)c(F)cc1F Show InChI InChI=1S/C21H20F3N5O/c22-16-11-18(24)17(23)9-14(16)8-15(25)10-20(30)28-6-7-29-19(12-28)26-21(27-29)13-4-2-1-3-5-13/h1-5,9,11,15H,6-8,10,12,25H2/t15-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of QPP				Bioorg Med Chem Lett 17: 5934-9 (2007) Article DOI: 10.1016/j.bmcl.2007.07.100 BindingDB Entry DOI: 10.7270/Q20C4VH0
					More data for this Ligand-Target Pair