BDBM50222023 CHEMBL389382::ethyl (4aS,5S,5aS,6R,8aR,9aS)-5-[(E)-2-[5-(2-methylphenyl)-2-pyridinyl]ethenyl]-decahydro-6-methyl-8-oxofuro[3,4-g]quinoline-1(2H)-carboxylate

SMILES: CCOC(=O)N1CCC[C@@H]2[C@@H]1C[C@@H]1[C@@H]([C@@H](C)OC1=O)[C@H]2\C=C\c1ccc(cn1)-c1ccccc1C

InChI Key: InChIKey=HJBJWUJDVYEQFK-FZVWNVEHSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50222023   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50222023 (CHEMBL389382 | ethyl (4aS,5S,5aS,6R,8aR,9aS)-5-[(E...) Show SMILES CCOC(=O)N1CCC[C@@H]2[C@@H]1C[C@@H]1[C@@H]([C@@H](C)OC1=O)[C@H]2\C=C\c1ccc(cn1)-c1ccccc1C Show InChI InChI=1S/C29H34N2O4/c1-4-34-29(33)31-15-7-10-23-24(27-19(3)35-28(32)25(27)16-26(23)31)14-13-21-12-11-20(17-30-21)22-9-6-5-8-18(22)2/h5-6,8-9,11-14,17,19,23-27H,4,7,10,15-16H2,1-3H3/b14-13+/t19-,23+,24+,25-,26+,27+/m1/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]haTRAP from PAR1 in human platelet membrane				J Med Chem 50: 5147-60 (2007) Article DOI: 10.1021/jm070704k BindingDB Entry DOI: 10.7270/Q2SN08PK
					More data for this Ligand-Target Pair