BDBM50223605 2-(5-phenyl-7-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-3-yl)acetonitrile::CHEMBL398647

SMILES: N#CCc1cnn2c(NCc3cccnc3)cc(nc12)-c1ccccc1

InChI Key: InChIKey=KGZGAYPHWQMSJX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223605   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50223605 (2-(5-phenyl-7-(pyridin-3-ylmethylamino)pyrazolo[1,...) Show SMILES N#CCc1cnn2c(NCc3cccnc3)cc(nc12)-c1ccccc1 Show InChI InChI=1S/C20H16N6/c21-9-8-17-14-24-26-19(23-13-15-5-4-10-22-12-15)11-18(25-20(17)26)16-6-2-1-3-7-16/h1-7,10-12,14,23H,8,13H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Schering-Plough Research Institute Curated by ChEMBL					Assay Description Inhibition of human GSK3beta				Bioorg Med Chem Lett 17: 6220-3 (2007) Article DOI: 10.1016/j.bmcl.2007.09.017 BindingDB Entry DOI: 10.7270/Q27M07ND
					More data for this Ligand-Target Pair