BDBM50223611 CHEMBL327525

SMILES: CC(C)(C)c1ccc(COc2cccc3[nH]nc(CN[C@H]4CN[C@H](CO)C4)c23)cc1

InChI Key: InChIKey=NLOLEHGTOFVKSZ-MOPGFXCFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223611   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA gyrase subunit A/B (Escherichia coli (strain K12))	BDBM50223611 (CHEMBL327525) Show SMILES CC(C)(C)c1ccc(COc2cccc3[nH]nc(CN[C@H]4CN[C@H](CO)C4)c23)cc1 Show InChI InChI=1S/C24H32N4O2/c1-24(2,3)17-9-7-16(8-10-17)15-30-22-6-4-5-20-23(22)21(28-27-20)13-26-18-11-19(14-29)25-12-18/h4-10,18-19,25-26,29H,11-15H2,1-3H3,(H,27,28)/t18-,19+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibitory activity against Escherichia coli DNA gyrase				Bioorg Med Chem Lett 14: 2857-62 (2004) BindingDB Entry DOI: 10.7270/Q2HH6N85
					More data for this Ligand-Target Pair