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SMILES: CS(=O)(=O)Nc1ccc(Sc2ccc(NC3=NCCN3)cc2)cc1

InChI Key: InChIKey=YMNXNKSMJMDKPY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50223862   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostacyclin receptor


(Homo sapiens (Human))		BDBM50223862
PNG
(CHEMBL9371)
Show SMILES CS(=O)(=O)Nc1ccc(Sc2ccc(NC3=NCCN3)cc2)cc1 |t:15|
Show InChI InChI=1S/C16H18N4O2S2/c1-24(21,22)20-13-4-8-15(9-5-13)23-14-6-2-12(3-7-14)19-16-17-10-11-18-16/h2-9,20H,10-11H2,1H3,(H2,17,18,19)
NCI pathway
Reactome pathway
KEGG

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PC sid
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Similars
PubMed
 79n/an/an/an/an/an/an/an/a



Roche Palo Alto

Curated by ChEMBL


Assay Description
Binding affinity towards prostacyclin receptor on rat NG-108-15 neuroblastoma cells, using [3H]iloprost as a radioligand

Bioorg Med Chem Lett 14: 1053-6 (2004)


BindingDB Entry DOI: 10.7270/Q2M90BVN
More data for this
Ligand-Target Pair