BDBM50225146 (E)-1-(7-fluoro-3-methyl-1,4-dioxy-quinoxalin-2-yl)-3-(4-hydroxy-3-methoxy-phenyl)-propenone::CHEMBL238171

SMILES: COc1cc(\C=C\C(=O)c2c(C)[n+]([O-])c3ccc(F)cc3[n+]2[O-])ccc1O

InChI Key: InChIKey=GYJZWFWHQZNIOB-XBXARRHUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50225146   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lipoxygenase-1 (Glycine max (soybean))	BDBM50225146 ((E)-1-(7-fluoro-3-methyl-1,4-dioxy-quinoxalin-2-yl...) Show SMILES COc1cc(\C=C\C(=O)c2c(C)[n+]([O-])c3ccc(F)cc3[n+]2[O-])ccc1O Show InChI InChI=1S/C19H15FN2O5/c1-11-19(22(26)15-10-13(20)5-6-14(15)21(11)25)17(24)8-4-12-3-7-16(23)18(9-12)27-2/h3-10,23H,1-2H3/b8-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Universidad de Navarra Curated by ChEMBL					Assay Description Inhibition of soybean lipoxygenase				Bioorg Med Chem Lett 17: 6439-43 (2007) Article DOI: 10.1016/j.bmcl.2007.10.002 BindingDB Entry DOI: 10.7270/Q2XW4JJ8
					More data for this Ligand-Target Pair