BDBM50226069 (S)-1-((3R,4R)-1-(4-(1,2,3-thiadiazol-4-yl)benzyl)-3-aminopyrrolidine-4-carbonyl)pyrrolidine-2-carbonitrile::CHEMBL249407

SMILES: N[C@H]1CN(Cc2ccc(cc2)-c2csnn2)C[C@H]1C(=O)N1CCC[C@H]1C#N

InChI Key: InChIKey=QGXOFEQXIHYJAU-BBWFWOEESA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50226069   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50226069 ((S)-1-((3R,4R)-1-(4-(1,2,3-thiadiazol-4-yl)benzyl)...) Show SMILES N[C@H]1CN(Cc2ccc(cc2)-c2csnn2)C[C@H]1C(=O)N1CCC[C@H]1C#N Show InChI InChI=1S/C19H22N6OS/c20-8-15-2-1-7-25(15)19(26)16-10-24(11-17(16)21)9-13-3-5-14(6-4-13)18-12-27-23-22-18/h3-6,12,15-17H,1-2,7,9-11,21H2/t15-,16+,17-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human DPP8				Bioorg Med Chem Lett 17: 6707-13 (2007) Article DOI: 10.1016/j.bmcl.2007.10.063 BindingDB Entry DOI: 10.7270/Q2ZS2W8B
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50226069 ((S)-1-((3R,4R)-1-(4-(1,2,3-thiadiazol-4-yl)benzyl)...) Show SMILES N[C@H]1CN(Cc2ccc(cc2)-c2csnn2)C[C@H]1C(=O)N1CCC[C@H]1C#N Show InChI InChI=1S/C19H22N6OS/c20-8-15-2-1-7-25(15)19(26)16-10-24(11-17(16)21)9-13-3-5-14(6-4-13)18-12-27-23-22-18/h3-6,12,15-17H,1-2,7,9-11,21H2/t15-,16+,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human DPP4				Bioorg Med Chem Lett 17: 6707-13 (2007) Article DOI: 10.1016/j.bmcl.2007.10.063 BindingDB Entry DOI: 10.7270/Q2ZS2W8B
					More data for this Ligand-Target Pair