BDBM50226429 CHEMBL237354::[L-arginyl]-N-(2,4-dichlorophenethyl)glycine 2,4-(dichlorophenethylamide)
SMILES: [#7]-[#6@@H](-[#6]-[#6]-[#6]\[#7]=[#6](\[#7])-[#7])-[#6](=O)-[#7](-[#6]-[#6]-c1ccc(Cl)cc1Cl)-[#6]-[#6](=O)-[#7]-[#6]-[#6]-c1ccc(Cl)cc1Cl
InChI Key: InChIKey=TYIVCKPBPCBXRJ-NRFANRHFSA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate [NMDA] receptor subunit epsilon 1/zeta 1 (Rattus norvegicus (Rat)-RAT) | BDBM50226429 (CHEMBL237354 | [L-arginyl]-N-(2,4-dichlorophenethy...) | PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Blockade of L-glutamate/glycine-activated rat NR1/NR2A NMDA receptor expressed in Xenopus oocytes | J Med Chem 50: 6133-43 (2007) Article DOI: 10.1021/jm070612v BindingDB Entry DOI: 10.7270/Q2FQ9WC0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Vanilloid receptor (Rattus norvegicus (rat)) | BDBM50226429 (CHEMBL237354 | [L-arginyl]-N-(2,4-dichlorophenethy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Barcelona Curated by ChEMBL | Assay Description Blockade of capsaicin-activated rat TRPV1 channel expressed in Xenopus oocytes | J Med Chem 50: 6133-43 (2007) Article DOI: 10.1021/jm070612v BindingDB Entry DOI: 10.7270/Q2FQ9WC0 | |||||||||||
More data for this Ligand-Target Pair |