BDBM50226908 CHEMBL30387

SMILES: CCc1nc(O)nc2ccc(OC)c(OC)c12

InChI Key: InChIKey=MAMULEXVYFXCEK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50226908   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50226908 (CHEMBL30387) Show SMILES CCc1nc(O)nc2ccc(OC)c(OC)c12 Show InChI InChI=1S/C12H14N2O3/c1-4-7-10-8(14-12(15)13-7)5-6-9(16-2)11(10)17-3/h5-6H,4H2,1-3H3,(H,13,14,15)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of canine cardiac fraction III cAMP phosphodiesterase (PDE 3) at 1.875 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair