BDBM50226909 CHEMBL31133

SMILES: COc1cc2nc(O)nc(-c3ccccc3)c2cc1OC

InChI Key: InChIKey=UKWHKNGMBFDJBU-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50226909   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50226909 (CHEMBL31133) Show SMILES COc1cc2nc(O)nc(-c3ccccc3)c2cc1OC Show InChI InChI=1S/C16H14N2O3/c1-20-13-8-11-12(9-14(13)21-2)17-16(19)18-15(11)10-6-4-3-5-7-10/h3-9H,1-2H3,(H,17,18,19)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibitory activity against canine cardiac fraction III cyclic AMP phosphodiesterase (PDE III) at 8.75 mg/kg intravenous dose				J Med Chem 30: 1421-6 (1987) BindingDB Entry DOI: 10.7270/Q21J9D0T
					More data for this Ligand-Target Pair