BDBM50227141 CHEMBL174483

SMILES: CCCCCc1ccc(\C=C\C(=O)Nc2cccc3c2oc(cc3=O)C(O)=O)cc1

InChI Key: InChIKey=HUNHHUAGWDAVDL-BUHFOSPRSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50227141   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteinyl leukotriene receptor 1 (GUINEA PIG)	BDBM50227141 (CHEMBL174483) Show SMILES CCCCCc1ccc(\C=C\C(=O)Nc2cccc3c2oc(cc3=O)C(O)=O)cc1 Show InChI InChI=1S/C24H23NO5/c1-2-3-4-6-16-9-11-17(12-10-16)13-14-22(27)25-19-8-5-7-18-20(26)15-21(24(28)29)30-23(18)19/h5,7-15H,2-4,6H2,1H3,(H,25,27)(H,28,29)/b14-13+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Goethe-University Frankfurt Curated by ChEMBL					Assay Description Displacement of [3H]ICI from cysteinyl leukotriene receptor 1 in Hartley guinea pig lung membrane after 30 mins by liquid scintillation counting meth...				J Med Chem 60: 5235-5266 (2017) Article DOI: 10.1021/acs.jmedchem.6b01287 BindingDB Entry DOI: 10.7270/Q2T43WDQ
					More data for this Ligand-Target Pair
Cysteinyl leukotriene receptor (Homo sapiens (Human))	BDBM50227141 (CHEMBL174483) Show SMILES CCCCCc1ccc(\C=C\C(=O)Nc2cccc3c2oc(cc3=O)C(O)=O)cc1 Show InChI InChI=1S/C24H23NO5/c1-2-3-4-6-16-9-11-17(12-10-16)13-14-22(27)25-19-8-5-7-18-20(26)15-21(24(28)29)30-23(18)19/h5,7-15H,2-4,6H2,1H3,(H,25,27)(H,28,29)/b14-13+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Ono Pharmaceutical Co., Ltd. Curated by ChEMBL					Assay Description Inhibition of LTC4 induced smooth muscle contraction of guinea pig ileum				J Med Chem 31: 84-91 (1988) BindingDB Entry DOI: 10.7270/Q20K2BSP
					More data for this Ligand-Target Pair