BDBM50227710 2-[4-(3'-ethoxy-2-methyl-biphenyl-4-yl)-3,6-dihydro-2H-pyridine-1-sulfonyl]-N-hydroxy-acetamide::CHEMBL255029

SMILES: CCOc1cccc(c1)-c1ccc(cc1C)C1=CCN(CC1)S(=O)(=O)CC(=O)NO

InChI Key: InChIKey=JYHCJUBSWRQINP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50227710   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stromelysin-1 (Homo sapiens (Human))	BDBM50227710 (2-[4-(3'-ethoxy-2-methyl-biphenyl-4-yl)-3,6-dihydr...) Show SMILES CCOc1cccc(c1)-c1ccc(cc1C)C1=CCN(CC1)S(=O)(=O)CC(=O)NO |t:18| Show InChI InChI=1S/C22H26N2O5S/c1-3-29-20-6-4-5-19(14-20)21-8-7-18(13-16(21)2)17-9-11-24(12-10-17)30(27,28)15-22(25)23-26/h4-9,13-14,26H,3,10-12,15H2,1-2H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50227710 (2-[4-(3'-ethoxy-2-methyl-biphenyl-4-yl)-3,6-dihydr...) Show SMILES CCOc1cccc(c1)-c1ccc(cc1C)C1=CCN(CC1)S(=O)(=O)CC(=O)NO |t:18| Show InChI InChI=1S/C22H26N2O5S/c1-3-29-20-6-4-5-19(14-20)21-8-7-18(13-16(21)2)17-9-11-24(12-10-17)30(27,28)15-22(25)23-26/h4-9,13-14,26H,3,10-12,15H2,1-2H3,(H,23,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	998	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair