BDBM50227734 CHEMBL254817::N-hydroxy-2-[4-(3'-methoxy-2-methyl-biphenyl-4-yl)-3,6-dihydro-2H-pyridine-1-sulfonyl]-acetamide

SMILES: COc1cccc(c1)-c1ccc(cc1C)C1=CCN(CC1)S(=O)(=O)CC(=O)NO

InChI Key: InChIKey=AFLLOSXTZXYSAK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50227734   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Stromelysin-1 (Homo sapiens (Human))	BDBM50227734 (CHEMBL254817 | N-hydroxy-2-[4-(3'-methoxy-2-methyl...) Show SMILES COc1cccc(c1)-c1ccc(cc1C)C1=CCN(CC1)S(=O)(=O)CC(=O)NO |t:17| Show InChI InChI=1S/C21H24N2O5S/c1-15-12-17(6-7-20(15)18-4-3-5-19(13-18)28-2)16-8-10-23(11-9-16)29(26,27)14-21(24)22-25/h3-8,12-13,25H,9-11,14H2,1-2H3,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP3				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM50227734 (CHEMBL254817 | N-hydroxy-2-[4-(3'-methoxy-2-methyl...) Show SMILES COc1cccc(c1)-c1ccc(cc1C)C1=CCN(CC1)S(=O)(=O)CC(=O)NO |t:17| Show InChI InChI=1S/C21H24N2O5S/c1-15-12-17(6-7-20(15)18-4-3-5-19(13-18)28-2)16-8-10-23(11-9-16)29(26,27)14-21(24)22-25/h3-8,12-13,25H,9-11,14H2,1-2H3,(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	222	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of MMP2				Bioorg Med Chem Lett 17: 6750-3 (2008) Article DOI: 10.1016/j.bmcl.2007.10.042 BindingDB Entry DOI: 10.7270/Q20K289K
					More data for this Ligand-Target Pair