BDBM50227767 2-(1-(quinolin-2-yl)piperazine-4-carboxamido)benzoic acid::CHEMBL252307

SMILES: OC(=O)c1ccccc1NC(=O)N1CCN(CC1)c1ccc2ccccc2n1

InChI Key: InChIKey=MFVAHNBRANJYPD-UHFFFAOYSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50227767   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50227767 (2-(1-(quinolin-2-yl)piperazine-4-carboxamido)benzo...) Show SMILES OC(=O)c1ccccc1NC(=O)N1CCN(CC1)c1ccc2ccccc2n1 Show InChI InChI=1S/C21H20N4O3/c26-20(27)16-6-2-4-8-18(16)23-21(28)25-13-11-24(12-14-25)19-10-9-15-5-1-3-7-17(15)22-19/h1-10H,11-14H2,(H,23,28)(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	5.90E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Agonist activity at human GPR106A by [35S]GTPgammaS binding assay				Bioorg Med Chem Lett 17: 6723-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.055 BindingDB Entry DOI: 10.7270/Q2R2114Q
					More data for this Ligand-Target Pair
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50227767 (2-(1-(quinolin-2-yl)piperazine-4-carboxamido)benzo...) Show SMILES OC(=O)c1ccccc1NC(=O)N1CCN(CC1)c1ccc2ccccc2n1 Show InChI InChI=1S/C21H20N4O3/c26-20(27)16-6-2-4-8-18(16)23-21(28)25-13-11-24(12-14-25)19-10-9-15-5-1-3-7-17(15)22-19/h1-10H,11-14H2,(H,23,28)(H,26,27)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]niacin from human GPR109A				Bioorg Med Chem Lett 17: 6723-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.055 BindingDB Entry DOI: 10.7270/Q2R2114Q
					More data for this Ligand-Target Pair