BDBM50227786 2-(1-(3,5-dichloropyridin-4-yl)piperazine-4-carboxamido)benzoic acid::CHEMBL252507

SMILES: OC(=O)c1ccccc1NC(=O)N1CCN(CC1)c1c(Cl)cncc1Cl

InChI Key: InChIKey=FJTJOZZGBJSIHY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50227786   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hydroxycarboxylic acid receptor 2 (Homo sapiens (Human))	BDBM50227786 (2-(1-(3,5-dichloropyridin-4-yl)piperazine-4-carbox...) Show SMILES OC(=O)c1ccccc1NC(=O)N1CCN(CC1)c1c(Cl)cncc1Cl Show InChI InChI=1S/C17H16Cl2N4O3/c18-12-9-20-10-13(19)15(12)22-5-7-23(8-6-22)17(26)21-14-4-2-1-3-11(14)16(24)25/h1-4,9-10H,5-8H2,(H,21,26)(H,24,25)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]niacin from human GPR109A				Bioorg Med Chem Lett 17: 6723-8 (2008) Article DOI: 10.1016/j.bmcl.2007.10.055 BindingDB Entry DOI: 10.7270/Q2R2114Q
					More data for this Ligand-Target Pair