BDBM50228022 CHEMBL404319::N-{1-(5-benzyl-1H-imidazol-2-yl)-2-[4-(1,1,3-trioxo-1lambda6-isothiazolidin-5-yl)-phenyl]-ethyl}-3-fluoro-benzenesulfonamide

SMILES: Fc1cccc(c1)S(=O)(=O)NC(Cc1ccc(cc1)C1CC(=O)NS1(=O)=O)c1ncc(Cc2ccccc2)[nH]1

InChI Key: InChIKey=PONPMHNRESGPEZ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50228022   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50228022 (CHEMBL404319 | N-{1-(5-benzyl-1H-imidazol-2-yl)-2-...) Show SMILES Fc1cccc(c1)S(=O)(=O)NC(Cc1ccc(cc1)C1CC(=O)NS1(=O)=O)c1ncc(Cc2ccccc2)[nH]1 |w:11.11| Show InChI InChI=1S/C27H25FN4O5S2/c28-21-7-4-8-23(15-21)38(34,35)31-24(27-29-17-22(30-27)13-18-5-2-1-3-6-18)14-19-9-11-20(12-10-19)25-16-26(33)32-39(25,36)37/h1-12,15,17,24-25,31H,13-14,16H2,(H,29,30)(H,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of TCPTP by pNPP assay				Bioorg Med Chem Lett 18: 66-71 (2008) Article DOI: 10.1016/j.bmcl.2007.11.012 BindingDB Entry DOI: 10.7270/Q2BV7GCQ
					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50228022 (CHEMBL404319 | N-{1-(5-benzyl-1H-imidazol-2-yl)-2-...) Show SMILES Fc1cccc(c1)S(=O)(=O)NC(Cc1ccc(cc1)C1CC(=O)NS1(=O)=O)c1ncc(Cc2ccccc2)[nH]1 |w:11.11| Show InChI InChI=1S/C27H25FN4O5S2/c28-21-7-4-8-23(15-21)38(34,35)31-24(27-29-17-22(30-27)13-18-5-2-1-3-6-18)14-19-9-11-20(12-10-19)25-16-26(33)32-39(25,36)37/h1-12,15,17,24-25,31H,13-14,16H2,(H,29,30)(H,32,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of PTP1B by pNPP assay				Bioorg Med Chem Lett 18: 66-71 (2008) Article DOI: 10.1016/j.bmcl.2007.11.012 BindingDB Entry DOI: 10.7270/Q2BV7GCQ
					More data for this Ligand-Target Pair