BDBM50228031 CHEMBL254513::N-{1-(1H-imidazol-2-yl)-2-[4-(1,1,3-trioxo-1lambda6-isothiazolidin-5-yl)-phenyl]-ethyl}-3-trifluoromethyl-benzenesulfonamide

SMILES: FC(F)(F)c1cccc(c1)S(=O)(=O)NC(Cc1ccc(cc1)C1CC(=O)NS1(=O)=O)c1ncc[nH]1

InChI Key: InChIKey=WHKVCJHBYDWODM-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50228031   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM50228031 (CHEMBL254513 | N-{1-(1H-imidazol-2-yl)-2-[4-(1,1,3...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)NC(Cc1ccc(cc1)C1CC(=O)NS1(=O)=O)c1ncc[nH]1 |w:22.23,14.14| Show InChI InChI=1S/C21H19F3N4O5S2/c22-21(23,24)15-2-1-3-16(11-15)34(30,31)27-17(20-25-8-9-26-20)10-13-4-6-14(7-5-13)18-12-19(29)28-35(18,32)33/h1-9,11,17-18,27H,10,12H2,(H,25,26)(H,28,29)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of TCPTP by pNPP assay				Bioorg Med Chem Lett 18: 66-71 (2008) Article DOI: 10.1016/j.bmcl.2007.11.012 BindingDB Entry DOI: 10.7270/Q2BV7GCQ
					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50228031 (CHEMBL254513 | N-{1-(1H-imidazol-2-yl)-2-[4-(1,1,3...) Show SMILES FC(F)(F)c1cccc(c1)S(=O)(=O)NC(Cc1ccc(cc1)C1CC(=O)NS1(=O)=O)c1ncc[nH]1 |w:22.23,14.14| Show InChI InChI=1S/C21H19F3N4O5S2/c22-21(23,24)15-2-1-3-16(11-15)34(30,31)27-17(20-25-8-9-26-20)10-13-4-6-14(7-5-13)18-12-19(29)28-35(18,32)33/h1-9,11,17-18,27H,10,12H2,(H,25,26)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Incyte Corporation Curated by ChEMBL					Assay Description Inhibition of PTP1B by pNPP assay				Bioorg Med Chem Lett 18: 66-71 (2008) Article DOI: 10.1016/j.bmcl.2007.11.012 BindingDB Entry DOI: 10.7270/Q2BV7GCQ
					More data for this Ligand-Target Pair