BDBM50228317 CHEMBL62833
SMILES: [H][C@@]12CCCN([C@@]1([H])C[C@@]1([H])N(CCc3cc(OC)ccc13)C2)S(C)(=O)=O
InChI Key: InChIKey=JKDBLHWERQWYKF-JCGIZDLHSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-2A adrenergic receptor [16-465]/Alpha-2B adrenergic receptor/Alpha-2C adrenergic receptor (RAT-NEONATAL RAT-Rattus norvegicus (rat)) | BDBM50228317![]() (CHEMBL62833) | PDB UniProtKB/SwissProt GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | 479 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Syntex Research Curated by ChEMBL | Assay Description In vitro inhibition of rat liver dihydrofolate reductase. | J Med Chem 32: 2034-6 (1989) BindingDB Entry DOI: 10.7270/Q2WH2S78 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-1A/Alpha-1B/Alpha-1D adrenergic receptor (Rattus norvegicus (rat)-Rattus norvegicus (Rat)) | BDBM50228317![]() (CHEMBL62833) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet ![]() | CHEMBL PC cid PC sid UniChem Similars | PubMed | <1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Syntex Research Curated by ChEMBL | Assay Description In vitro inhibition of dihydrofolate reductase of Escherichia coli | J Med Chem 32: 2034-6 (1989) BindingDB Entry DOI: 10.7270/Q2WH2S78 | |||||||||||
More data for this Ligand-Target Pair |