BDBM50228446 CHEMBL125853

SMILES: CC1CC(=O)NN=C1c1ccc2OC(C)C(=O)N(C3CCCC3)c2c1

InChI Key: InChIKey=KFAKFQMLQYKMLO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50228446   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B (Homo sapiens (Human))	BDBM50228446 (CHEMBL125853) Show SMILES CC1CC(=O)NN=C1c1ccc2OC(C)C(=O)N(C3CCCC3)c2c1 |c:6| Show InChI InChI=1S/C19H23N3O3/c1-11-9-17(23)20-21-18(11)13-7-8-16-15(10-13)22(14-5-3-4-6-14)19(24)12(2)25-16/h7-8,10-12,14H,3-6,9H2,1-2H3,(H,20,23)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
R.W. Johnson Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of cardiac phosphodiesterase-3 isolated from canine heart.				J Med Chem 33: 380-6 (1990) BindingDB Entry DOI: 10.7270/Q241708F
					More data for this Ligand-Target Pair