BDBM50229794 CHEMBL90176
SMILES: CC(C)CN1CCN(CC1)C(=O)CCCOc1ccc2[nH]c3nc(O)nc3cc2c1
InChI Key: InChIKey=RZJZOCXUKKUZIW-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Phosphodiesterase 3 (Homo sapiens (Human)) | BDBM50229794 (CHEMBL90176) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL | Assay Description Inhibition of human platelet c-AMP phosphodiesterase PDE 3 | J Med Chem 35: 2688-96 (1992) BindingDB Entry DOI: 10.7270/Q2PN97WB | |||||||||||
More data for this Ligand-Target Pair |