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SMILES: Oc1nc2cc3cc(OCCCC(=O)N4CCN(CC4)c4ncccn4)ccc3[nH]c2n1

InChI Key: InChIKey=GPIHWBUAHFKNRT-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229808   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B


(Homo sapiens (Human))		BDBM50229808
PNG
(CHEMBL329412)
Show SMILES Oc1nc2cc3cc(OCCCC(=O)N4CCN(CC4)c4ncccn4)ccc3[nH]c2n1
Show InChI InChI=1S/C22H23N7O3/c30-19(28-8-10-29(11-9-28)21-23-6-2-7-24-21)3-1-12-32-16-4-5-17-15(13-16)14-18-20(25-17)27-22(31)26-18/h2,4-7,13-14H,1,3,8-12H2,(H2,25,26,27,31)
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PC cid
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Similars
PubMed
n/an/a 7n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibition of human platelet c-AMP phosphodiesterase PDE 3

J Med Chem 35: 2688-96 (1992)


BindingDB Entry DOI: 10.7270/Q2PN97WB
More data for this
Ligand-Target Pair