BDBM50229815 CHEMBL90515

SMILES: CN(CCc1ccccn1)C(=O)CCCOc1ccc2[nH]c3nc(O)nc3cc2c1

InChI Key: InChIKey=LILSLOPBWKSUKL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229815   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase A/B (Homo sapiens (Human))	BDBM50229815 (CHEMBL90515) Show SMILES CN(CCc1ccccn1)C(=O)CCCOc1ccc2[nH]c3nc(O)nc3cc2c1 Show InChI InChI=1S/C22H23N5O3/c1-27(11-9-16-5-2-3-10-23-16)20(28)6-4-12-30-17-7-8-18-15(13-17)14-19-21(24-18)26-22(29)25-19/h2-3,5,7-8,10,13-14H,4,6,9,11-12H2,1H3,(H2,24,25,26,29)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human platelet c-AMP phosphodiesterase PDE 3				J Med Chem 35: 2688-96 (1992) BindingDB Entry DOI: 10.7270/Q2PN97WB
					More data for this Ligand-Target Pair