BDBM50229831 CHEMBL327882

SMILES: COc1ccc(CN2CCN(CC2)C(=O)CCCOc2ccc3[nH]c4nc(O)nc4cc3c2)cc1

InChI Key: InChIKey=KIRSBLHEWGQGSV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50229831   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cGMP-inhibited 3',5'-cyclic phosphodiesterase A/B (Homo sapiens (Human))	BDBM50229831 (CHEMBL327882) Show SMILES COc1ccc(CN2CCN(CC2)C(=O)CCCOc2ccc3[nH]c4nc(O)nc4cc3c2)cc1 Show InChI InChI=1S/C26H29N5O4/c1-34-20-6-4-18(5-7-20)17-30-10-12-31(13-11-30)24(32)3-2-14-35-21-8-9-22-19(15-21)16-23-25(27-22)29-26(33)28-23/h4-9,15-16H,2-3,10-14,17H2,1H3,(H2,27,28,29,33)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human platelet c-AMP phosphodiesterase PDE 3				J Med Chem 35: 2688-96 (1992) BindingDB Entry DOI: 10.7270/Q2PN97WB
					More data for this Ligand-Target Pair