BDBM50231560 CHEMBL1203083

SMILES: Cl.Oc1nc2cc3cc(OCCCNC(=O)N4CCN(Cc5ccccc5)CC4)ccc3[nH]c2n1

InChI Key: InChIKey=RLOJJOHSNSPOOA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231560   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 3 (Homo sapiens (Human))	BDBM50231560 (CHEMBL1203083) Show SMILES Cl.Oc1nc2cc3cc(OCCCNC(=O)N4CCN(Cc5ccccc5)CC4)ccc3[nH]c2n1 Show InChI InChI=1S/C25H28N6O3/c32-24-28-22-16-19-15-20(7-8-21(19)27-23(22)29-24)34-14-4-9-26-25(33)31-12-10-30(11-13-31)17-18-5-2-1-3-6-18/h1-3,5-8,15-16H,4,9-14,17H2,(H,26,33)(H2,27,28,29,32)	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human platelet aggregation cAMP PDE in vitro				J Med Chem 36: 3251-64 (1993) Article DOI: 10.1021/jm00074a005 BindingDB Entry DOI: 10.7270/Q289184P
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