BDBM50231781 CHEMBL4090528

SMILES: C(Sc1nc(Sc2ccccn2)c2nnn(Cc3ccccc3)c2n1)c1ccccc1

InChI Key: InChIKey=TXGIXVXSJROFEA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50231781   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific histone demethylase 1A (Homo sapiens (Human))	BDBM50231781 (CHEMBL4090528) Show SMILES C(Sc1nc(Sc2ccccn2)c2nnn(Cc3ccccc3)c2n1)c1ccccc1 Show InChI InChI=1S/C23H18N6S2/c1-3-9-17(10-4-1)15-29-21-20(27-28-29)22(31-19-13-7-8-14-24-19)26-23(25-21)30-16-18-11-5-2-6-12-18/h1-14H,15-16H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	564	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Technology of Drug Preparation (Zhengzhou University) Curated by ChEMBL					Assay Description Inhibition of full length recombinant LSD1 (unknown origin) expressed in Escherichia coli BL21(DE) using H3K4me2 as substrate by fluorescence assay				ACS Med Chem Lett 8: 384-389 (2017) BindingDB Entry DOI: 10.7270/Q2FQ9ZV3
					More data for this Ligand-Target Pair