BDBM50232135 (R)-1-(5-tert-butyl-2,3-dihydro-1H-inden-1-yl)-2-cyano-3-(1H-indazol-4-yl)guanidine::CHEMBL3085384

SMILES: CC(C)(C)c1ccc2[C@@H](CCc2c1)N\C(Nc1cccc2[nH]ncc12)=N\C#N

InChI Key: InChIKey=DEGNPZKKRORGOM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50232135   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM50232135 ((R)-1-(5-tert-butyl-2,3-dihydro-1H-inden-1-yl)-2-c...) Show SMILES CC(C)(C)c1ccc2[C@@H](CCc2c1)N\C(Nc1cccc2[nH]ncc12)=N\C#N |r| Show InChI InChI=1S/C22H24N6/c1-22(2,3)15-8-9-16-14(11-15)7-10-19(16)27-21(24-13-23)26-18-5-4-6-20-17(18)12-25-28-20/h4-6,8-9,11-12,19H,7,10H2,1-3H3,(H,25,28)(H2,24,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories Curated by ChEMBL					Assay Description Blockade of human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux				J Med Chem 51: 392-5 (2008) Article DOI: 10.1021/jm701007g BindingDB Entry DOI: 10.7270/Q218367F
					More data for this Ligand-Target Pair