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SMILES: O=C(NC1CCc2cccnc12)Nc1cccc2[nH]ncc12

InChI Key: InChIKey=MNELSNAYLAVDIE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50232139   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transient receptor potential cation channel subfamily V member 1


(Homo sapiens (Human))		BDBM50232139
PNG
(1-(6,7-dihydro-5H-[1]pyridin-7-yl)-3-(1H-indazol-4...)
Show SMILES O=C(NC1CCc2cccnc12)Nc1cccc2[nH]ncc12 |w:3.2|
Show InChI InChI=1S/C16H15N5O/c22-16(19-12-4-1-5-13-11(12)9-18-21-13)20-14-7-6-10-3-2-8-17-15(10)14/h1-5,8-9,14H,6-7H2,(H,18,21)(H2,19,20,22)
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Article
PubMed
n/an/a 1.35E+3n/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Blockade of human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium flux

J Med Chem 51: 392-5 (2008)


Article DOI: 10.1021/jm701007g
BindingDB Entry DOI: 10.7270/Q218367F
More data for this
Ligand-Target Pair