BDBM50232522 CHEMBL4065397

SMILES: COc1ccc(cc1COc1ccc(CCC(O)=O)cc1C)C(F)(F)F

InChI Key: InChIKey=UUOBFCXKSUXTJS-UHFFFAOYSA-N

Data: 10 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50232522   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Free fatty acid receptor 1 (Rattus norvegicus)	BDBM50232522 (CHEMBL4065397) Show SMILES COc1ccc(cc1COc1ccc(CCC(O)=O)cc1C)C(F)(F)F Show InChI InChI=1S/C19H19F3O4/c1-12-9-13(4-8-18(23)24)3-6-16(12)26-11-14-10-15(19(20,21)22)5-7-17(14)25-2/h3,5-7,9-10H,4,8,11H2,1-2H3,(H,23,24)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at rat FFA1 receptor				Bioorg Med Chem Lett 27: 1278-1283 (2017) BindingDB Entry DOI: 10.7270/Q2ZK5JWB
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50232522 (CHEMBL4065397) Show SMILES COc1ccc(cc1COc1ccc(CCC(O)=O)cc1C)C(F)(F)F Show InChI InChI=1S/C19H19F3O4/c1-12-9-13(4-8-18(23)24)3-6-16(12)26-11-14-10-15(19(20,21)22)5-7-17(14)25-2/h3,5-7,9-10H,4,8,11H2,1-2H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.18E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at human FFA1 receptor expressed in human U2OS cells co-expressing Galpha16 assessed as calcium mobilization by Fluo-4 dye based FLI...				Bioorg Med Chem Lett 27: 1278-1283 (2017) BindingDB Entry DOI: 10.7270/Q2ZK5JWB
					More data for this Ligand-Target Pair
G-protein coupled receptor 120 (Homo sapiens (Human))	BDBM50232522 (CHEMBL4065397) Show SMILES COc1ccc(cc1COc1ccc(CCC(O)=O)cc1C)C(F)(F)F Show InChI InChI=1S/C19H19F3O4/c1-12-9-13(4-8-18(23)24)3-6-16(12)26-11-14-10-15(19(20,21)22)5-7-17(14)25-2/h3,5-7,9-10H,4,8,11H2,1-2H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	316	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at human FFA4 receptor expressed in human U2OS cells co-expressing Galpha16 assessed as calcium mobilization by Fluo-4 dye based FLI...				Bioorg Med Chem Lett 27: 1278-1283 (2017) BindingDB Entry DOI: 10.7270/Q2ZK5JWB
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Homo sapiens (Human))	BDBM50232522 (CHEMBL4065397) Show SMILES COc1ccc(cc1COc1ccc(CCC(O)=O)cc1C)C(F)(F)F Show InChI InChI=1S/C19H19F3O4/c1-12-9-13(4-8-18(23)24)3-6-16(12)26-11-14-10-15(19(20,21)22)5-7-17(14)25-2/h3,5-7,9-10H,4,8,11H2,1-2H3,(H,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	1.26E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at human FFA1 receptor expressed in human U2OS cells co-expressing Galpha16 assessed as calcium mobilization by Fluo-4 dye based FLI...				Bioorg Med Chem Lett 27: 1278-1283 (2017) BindingDB Entry DOI: 10.7270/Q2ZK5JWB
					More data for this Ligand-Target Pair
Free fatty acid receptor 3 (Homo sapiens (Human))	BDBM50232522 (CHEMBL4065397) Show SMILES COc1ccc(cc1COc1ccc(CCC(O)=O)cc1C)C(F)(F)F Show InChI InChI=1S/C19H19F3O4/c1-12-9-13(4-8-18(23)24)3-6-16(12)26-11-14-10-15(19(20,21)22)5-7-17(14)25-2/h3,5-7,9-10H,4,8,11H2,1-2H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at human FFA3 receptor by FLIPR assay				Bioorg Med Chem Lett 27: 1278-1283 (2017) BindingDB Entry DOI: 10.7270/Q2ZK5JWB
					More data for this Ligand-Target Pair
Omega-3 fatty acid receptor 1 (Mus musculus)	BDBM50232522 (CHEMBL4065397) Show SMILES COc1ccc(cc1COc1ccc(CCC(O)=O)cc1C)C(F)(F)F Show InChI InChI=1S/C19H19F3O4/c1-12-9-13(4-8-18(23)24)3-6-16(12)26-11-14-10-15(19(20,21)22)5-7-17(14)25-2/h3,5-7,9-10H,4,8,11H2,1-2H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	70	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at mouse FFA4 receptor				Bioorg Med Chem Lett 27: 1278-1283 (2017) BindingDB Entry DOI: 10.7270/Q2ZK5JWB
					More data for this Ligand-Target Pair
Free fatty acid receptor 4 (Rattus norvegicus)	BDBM50232522 (CHEMBL4065397) Show SMILES COc1ccc(cc1COc1ccc(CCC(O)=O)cc1C)C(F)(F)F Show InChI InChI=1S/C19H19F3O4/c1-12-9-13(4-8-18(23)24)3-6-16(12)26-11-14-10-15(19(20,21)22)5-7-17(14)25-2/h3,5-7,9-10H,4,8,11H2,1-2H3,(H,23,24)	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	230	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at rat FFA4 receptor				Bioorg Med Chem Lett 27: 1278-1283 (2017) BindingDB Entry DOI: 10.7270/Q2ZK5JWB
					More data for this Ligand-Target Pair
Free fatty acid receptor 1 (Mus musculus)	BDBM50232522 (CHEMBL4065397) Show SMILES COc1ccc(cc1COc1ccc(CCC(O)=O)cc1C)C(F)(F)F Show InChI InChI=1S/C19H19F3O4/c1-12-9-13(4-8-18(23)24)3-6-16(12)26-11-14-10-15(19(20,21)22)5-7-17(14)25-2/h3,5-7,9-10H,4,8,11H2,1-2H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	6.21E+3	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at mouse FFA1 receptor				Bioorg Med Chem Lett 27: 1278-1283 (2017) BindingDB Entry DOI: 10.7270/Q2ZK5JWB
					More data for this Ligand-Target Pair
Free fatty acid receptor 2 (Homo sapiens (Human))	BDBM50232522 (CHEMBL4065397) Show SMILES COc1ccc(cc1COc1ccc(CCC(O)=O)cc1C)C(F)(F)F Show InChI InChI=1S/C19H19F3O4/c1-12-9-13(4-8-18(23)24)3-6-16(12)26-11-14-10-15(19(20,21)22)5-7-17(14)25-2/h3,5-7,9-10H,4,8,11H2,1-2H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.53E+4	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at human FFA2 receptor by FLIPR assay				Bioorg Med Chem Lett 27: 1278-1283 (2017) BindingDB Entry DOI: 10.7270/Q2ZK5JWB
					More data for this Ligand-Target Pair
G-protein coupled receptor 120 (Homo sapiens (Human))	BDBM50232522 (CHEMBL4065397) Show SMILES COc1ccc(cc1COc1ccc(CCC(O)=O)cc1C)C(F)(F)F Show InChI InChI=1S/C19H19F3O4/c1-12-9-13(4-8-18(23)24)3-6-16(12)26-11-14-10-15(19(20,21)22)5-7-17(14)25-2/h3,5-7,9-10H,4,8,11H2,1-2H3,(H,23,24)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	299	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Agonist activity at human FFA4 receptor expressed in human U2OS cells co-expressing Galpha16 assessed as calcium mobilization by Fluo-4 dye based FLI...				Bioorg Med Chem Lett 27: 1278-1283 (2017) BindingDB Entry DOI: 10.7270/Q2ZK5JWB
					More data for this Ligand-Target Pair