BDBM50232556 CHEMBL4095176

SMILES: C[C@H](NC(=O)c1cc(Cl)ccc1Oc1cccc(Cl)c1)c1ccc(cc1)C(O)=O

InChI Key: InChIKey=PSRWNAXGTLCGIF-ZDUSSCGKSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50232556   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP4 subtype (Homo sapiens (Human))	BDBM50232556 (CHEMBL4095176) Show SMILES C[C@H](NC(=O)c1cc(Cl)ccc1Oc1cccc(Cl)c1)c1ccc(cc1)C(O)=O |r| Show InChI InChI=1S/C22H17Cl2NO4/c1-13(14-5-7-15(8-6-14)22(27)28)25-21(26)19-12-17(24)9-10-20(19)29-18-4-2-3-16(23)11-18/h2-13H,1H3,(H,25,26)(H,27,28)/t13-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
AskAt Inc. Curated by ChEMBL					Assay Description Antagonist activity at human EP4 receptor expressed in HEK293 cells assessed as inhibition of PGE2-induced cAMP level by HTS assay				Bioorg Med Chem Lett 27: 1186-1192 (2017) BindingDB Entry DOI: 10.7270/Q2Q242F0
					More data for this Ligand-Target Pair