BDBM50233015 CHEMBL252646::N-((1S,13bR)-7-chloro-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-2,2,2-trifluoro-acetamide

SMILES: FC(F)(F)C(=O)N[C@H]1CCCN2[C@@H]1c1ccccc1Oc1cc(Cl)ccc21

InChI Key: InChIKey=AHHXFENSECPMBT-SUMWQHHRSA-N

Data: 1 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50233015   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50233015 (CHEMBL252646 | N-((1S,13bR)-7-chloro-1,3,4,13b-tet...) Show SMILES FC(F)(F)C(=O)N[C@H]1CCCN2[C@@H]1c1ccccc1Oc1cc(Cl)ccc21 Show InChI InChI=1S/C19H16ClF3N2O2/c20-11-7-8-14-16(10-11)27-15-6-2-1-4-12(15)17-13(5-3-9-25(14)17)24-18(26)19(21,22)23/h1-2,4,6-8,10,13,17H,3,5,9H2,(H,24,26)/t13-,17+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	993	n/a	n/a	n/a	n/a
N.V. Organon Curated by ChEMBL					Assay Description Agonist activity at progesterone receptor expressed in CHO cells by luciferase assay				Bioorg Med Chem Lett 18: 1461-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.065 BindingDB Entry DOI: 10.7270/Q2BK1C3V
					More data for this Ligand-Target Pair
Progesterone receptor (Homo sapiens (Human))	BDBM50233015 (CHEMBL252646 | N-((1S,13bR)-7-chloro-1,3,4,13b-tet...) Show SMILES FC(F)(F)C(=O)N[C@H]1CCCN2[C@@H]1c1ccccc1Oc1cc(Cl)ccc21 Show InChI InChI=1S/C19H16ClF3N2O2/c20-11-7-8-14-16(10-11)27-15-6-2-1-4-12(15)17-13(5-3-9-25(14)17)24-18(26)19(21,22)23/h1-2,4,6-8,10,13,17H,3,5,9H2,(H,24,26)/t13-,17+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
N.V. Organon Curated by ChEMBL					Assay Description Inhibition of progesterone receptor expressed in CHO cells by luciferase assay				Bioorg Med Chem Lett 18: 1461-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.065 BindingDB Entry DOI: 10.7270/Q2BK1C3V
					More data for this Ligand-Target Pair