BDBM50233018 CHEMBL401627::N-((1S,13bR)-6-chloro-1,3,4,13b-tetrahydro-2H-9-oxa-4a-aza-tribenzo[a,c,e]cyclohepten-1-yl)-2,2,2-trifluoro-N-methyl-acetamide

SMILES: CN([C@H]1CCCN2[C@@H]1c1ccccc1Oc1ccc(Cl)cc21)C(=O)C(F)(F)F

InChI Key: InChIKey=FWZOQLQKXSHTIN-KBXCAEBGSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50233018   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Progesterone receptor (Homo sapiens (Human))	BDBM50233018 (CHEMBL401627 | N-((1S,13bR)-6-chloro-1,3,4,13b-tet...) Show SMILES CN([C@H]1CCCN2[C@@H]1c1ccccc1Oc1ccc(Cl)cc21)C(=O)C(F)(F)F Show InChI InChI=1S/C20H18ClF3N2O2/c1-25(19(27)20(22,23)24)14-6-4-10-26-15-11-12(21)8-9-17(15)28-16-7-3-2-5-13(16)18(14)26/h2-3,5,7-9,11,14,18H,4,6,10H2,1H3/t14-,18+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	450	n/a	n/a	n/a	n/a
N.V. Organon Curated by ChEMBL					Assay Description Agonist activity at progesterone receptor expressed in CHO cells by luciferase assay				Bioorg Med Chem Lett 18: 1461-7 (2008) Article DOI: 10.1016/j.bmcl.2007.12.065 BindingDB Entry DOI: 10.7270/Q2BK1C3V
					More data for this Ligand-Target Pair