BDBM50233828 CHEMBL4062047

SMILES: C\C(=C/C(=O)Nc1ccc([123I])cc1C(O)=O)c1ccc2ccccc2c1

InChI Key: InChIKey=DGDGGEUSRBDFSP-JLHYYAGUSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50233828   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Telomerase reverse transcriptase (Homo sapiens (Human))	BDBM50233828 (CHEMBL4062047) Show SMILES C\C(=C/C(=O)Nc1ccc([123I])cc1C(O)=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C21H16INO3/c1-13(15-7-6-14-4-2-3-5-16(14)11-15)10-20(24)23-19-9-8-17(22)12-18(19)21(25)26/h2-12H,1H3,(H,23,24)(H,25,26)/b13-10+	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	3.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Oxford Curated by ChEMBL					Assay Description Inhibition of telomerase activity (unknown origin) in cell free system using sulforhodamine labeled primer measured after 30 mins by telomerase repea...				Eur J Med Chem 125: 117-129 (2017) BindingDB Entry DOI: 10.7270/Q2NS0X5V
					More data for this Ligand-Target Pair