BDBM50233936 CHEMBL4083210

SMILES: Cc1c(Sc2cccc(n2)C(O)=O)c2ccccc2n1-c1ccccc1

InChI Key: InChIKey=LQMVWXSGABJAGE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50233936   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (Homo sapiens (Human))	BDBM50233936 (CHEMBL4083210) Show SMILES Cc1c(Sc2cccc(n2)C(O)=O)c2ccccc2n1-c1ccccc1 Show InChI InChI=1S/C21H16N2O2S/c1-14-20(26-19-13-7-11-17(22-19)21(24)25)16-10-5-6-12-18(16)23(14)15-8-3-2-4-9-15/h2-13H,1H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Strathclyde Curated by ChEMBL					Assay Description Inhibition of human ATX expressed in HEK293 Flp-In cells using LPC as substrate measured every 30 sec for 90 mins by fluorescence assay				J Med Chem 60: 722-748 (2017) BindingDB Entry DOI: 10.7270/Q2MW2KCW
					More data for this Ligand-Target Pair