BDBM50234313 CHEMBL4102399

SMILES: [O-][N+](=O)c1ccccc1Nc1nnc(o1)-c1c[nH]c2ccccc12

InChI Key: InChIKey=KMBFUJJRYOMMRA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50234313   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM50234313 (CHEMBL4102399) Show SMILES [O-][N+](=O)c1ccccc1Nc1nnc(o1)-c1c[nH]c2ccccc12 Show InChI InChI=1S/C16H11N5O3/c22-21(23)14-8-4-3-7-13(14)18-16-20-19-15(24-16)11-9-17-12-6-2-1-5-10(11)12/h1-9,17H,(H,18,20)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cardiff University Curated by ChEMBL					Assay Description Inhibition of biotinylated Bim peptide binding to His-tagged Bcl-2 (unknown origin) preincubated for 1 hr followed by biotinylated Bim peptide additi...				Bioorg Med Chem Lett 27: 1037-1040 (2017) BindingDB Entry DOI: 10.7270/Q28C9ZG5
					More data for this Ligand-Target Pair